Assessment of the genotoxic and antigenotoxic activities of the aqueous solution of the Caesalpinia ferrea (tul.) Martius fruit (jucá)

Autores/as

  • Kênia dos Santos Oliveira Pontifícia Universidade Católica de Goiás
  • Susy Ricardo Lemes Universidade Federal de Goiás
  • Mariah de Barros Tondato Pontifícia Universidade Católica de Goiás
  • Raphaela Matsuola Alves Pontifícia Universidade Católica de Goiás
  • Maria Alice Montes de Sousa Pontifícia Universidade Católica de Goiás
  • Lilhian Alves de Araújo Pontifícia Universidade Católica de Goiás
  • Cristiene Costa Carneiro Universidade Federal de Goiás
  • Lee Chen Chen Universidade Federal de Goiás
  • Paulo Roberto Melo Reis Pontifícia Universidade Católica de Goiás

Resumen

Introduction: The inner bark of Caesalpinia ferrea, popularly known as jucá, has been used in alternative medicine to treat wounds, bruises, asthma and chronic cough. Furthermore, the fruits of this species are used as antidiarrheals, decongestants and in healing, and their roots as antipyretics. Objective: In order to assess the possible genotoxic and antigenotoxic activities of the aqueous solution of the jucá fruit. Materials and Methods: This study used the Ames test in Salmonella typhimurium strains and the micronucleus test in mouse bone marrow. Results: The Ames test results for the jucá solution were not mutagenic in the Salmonella typhimurium TA100 strain in any of the doses tested. However, a protective effect against the action of sodium azide was shown in the TA100 strain at all the doses used. The micronucleus test indicated that the jucá aqueous solution showed no mutagenic or antimutagenic effect.

Descargas

Los datos de descargas todavía no están disponibles.

Descargas

Publicado

2019-12-28

Cómo citar

1.
Oliveira K dos S, Lemes SR, Tondato M de B, Alves RM, de Sousa MAM, de Araújo LA, et al. Assessment of the genotoxic and antigenotoxic activities of the aqueous solution of the Caesalpinia ferrea (tul.) Martius fruit (jucá). Rev cuba plant med [Internet]. 28 de diciembre de 2019 [citado 12 de julio de 2025];24(3). Disponible en: https://revplantasmedicinales.sld.cu/index.php/pla/article/view/694

Número

Sección

Artículos originales